Integra 44 Sodium hydroxymethylglycinate 70161-44-3 International Specialty Products Preservatives / Biocides / Fungicides ADHESIVE >> Water-based This highly convenient liquid biocide provides broad spectrum antimicrobial activity. Integra 44 is unusual in that it remains active at alkaline pH. Integra 44 is active between pH 3.5 to 12, providing very wide flexibility for the formulator. Integra 44 is ideal for water-based applications. Integra® 44 Aqueous solution of Sodium hydroxymethylglycinate. Derived from Glycine - a naturally occurring amino acid. Broad spectrum antimicrobial activity. Effective against bacteria and fungi. Active from pH 3.5 to pH 12. Easy to use and safe to handle. Excellent for water based applications such as adhesives Adhesives based on starches, latexes and natural or synthetic gums can be preserved with Integra 44 at levels up to 1.0% as supplied. Integra 44 is particularly effective in starch based adhesives, which are normally alkaline pH. Integra® 44 is very active against Gram-negative and Gram-positive bacteria, but is also effective against fungi. Integra 44 is particularly effective against Pseudomonas aeruginosa, a common spoilage organism. Broad spectrum activity Most microorganisms require an environment with a pH between 5 and 9. Sometimes a species will survive up to pH 12. Integra 44 remains active from pH 3.5 to pH 12 giving the formulator very wide pH flexibility. Compatibility Integra 44 is not inactivated by surfactant systems and most common formulations. Color changes have been observed, however, with fragrances containing citral, although the antimicrobial properties are not affected. Effective at low concentrations Typical formulations use Integra 44 at low concentrations, usually 0.2 - 1.0% as supplied, thereby providing cost effective preservation. Ease of handling Integra 44 is supplied as a 50% aqueous solution allowing for easier handling in manufacturing when compared to powdered preservatives. Integra 44 also shows excellent water solubility and low oil solubility, so it will remain in the water phase where it acts against microorganisms. Low order of toxicity The information provided below are typical properties of Integra 44 and are not necessarily specifications. Aqueous solution of sodium hydroxymethylglycinate. Used as a bactericide and a fungicide for water-based applications such as adhesives based on starches, latexes and natural or synthetic gums. Offers broad spectrum antimicrobial activity, compatibility with surfactant systems and most common formulations and low order of toxicity. Use level: up to 1.0% as supplied.